Ningbo University: Wearable biosensor for continuous analysis of sweat glucose in resting state by stimulating sweat secretion through electric heating film

Diabetes is a common chronic metabolic disease characterized by hyperglycemia. It has become one of the major causes of death in the world. Hundreds of millions of people are affected worldwide, and about 1.6 million people die every year. Therefore, regular and accurate monitoring of blood glucose is crucial for the diagnosis and management of diabetes. Nowadays, portable blood glucose meters (BGMs) have been widely used for home self testing, accurately assessing blood glucose levels through fingertip blood collection.However, due to the structure and sensing principle of these devices, users have to frequently suffer from invasive pain and potential infection risks, especially for diabetes patients whose wounds are not easy to heal. In addition, traditional blood glucose meters cannot perform continuous monitoring. Therefore, as an alternative solution with great potential, wearable sensors are gradually gaining attention and meeting the needs of modern personalized medicine. Wearable sensors can be combined with the skin through clothing, glasses, or transdermal patches to provide a more convenient user experience. With the integration of biosensing modules, wearable sensors can not only monitor physiological data, but also non invasively detect metabolites, ions, and biomarkers. However, this technology still faces some challenges, such as how to meet the needs of people of different age groups and activity states. Therefore, further research and optimization of wearable biosensors will help achieve more personalized health diagnosis and daily care.

Recently, Assistant Researcher Yu Zhenzhong from the School of Materials Science and Chemical Engineering at Ningbo University reported a new wearable biosensor based on electric thermal thin film stimulation of sweat secretion, which can achieve quantitative analysis of glucose in human sweat at rest. The related results were published in the international authoritative chemical journal Analytical Chemistry (DOI: 10.1021/acs. analytical. 4c04271) under the title "Wearable Patch Biosensor through Electrothermal Film Simulated Sweat Secret for Continuous Sweat Glucose Analysis at Rest". Liu Yuting, a master's student at Ningbo University, is the first author of this paper.